How does physical activity influence saffron's effects on health?

How does physical activity influence saffron's effects on health

Physical activity positively influences saffron’s effects on health by enhancing systemic circulation, reducing inflammation, and improving metabolic function, which together support the antioxidant and neuroprotective benefits saffron provides.

How Physical Activity Supports Saffron’s Effects

• Improved blood flow: Regular exercise promotes better circulation, including to the eyes and brain, helping deliver saffron’s active compounds more effectively to target tissues.

• Reduced inflammation: Physical activity lowers systemic inflammation, augmenting saffron’s anti-inflammatory properties that protect against oxidative stress and cellular damage.

• Enhanced metabolic health: Exercise improves insulin sensitivity, cardiovascular health, and lipid profiles, reducing risk factors that contribute to chronic diseases saffron helps mitigate, such as age-related macular degeneration (AMD) and neurodegeneration.

• Neuroprotection: Both saffron and physical activity independently support brain and eye health through antioxidant and neuroprotective mechanisms, likely providing additive or synergistic benefits when combined.

Summary

Physical activity complements saffron supplementation by improving circulation, reducing inflammation, and enhancing metabolic and neuroprotective effects, ultimately helping extend saffron's health benefits, especially in conditions like AMD and cognitive decline.

PMID: 35548173

PMID: 32379589

https://doi.org/10.1016/j.biopha.2020.110995

Health Research article